TNM classification for renal cell carcinoma
Tumor classification
Tx: Primary tumor cannot be assessed
T0: No evidence of primary tumor
T1a: Tumor limited to kidney, ≤ 4 cm in greatest dimension
T1b: Tumor limited to kidney, > 4 cm but ≤ 7 cm in greatest dimension
T2a: Tumor limited to kidney, > 7 cm but ≤ 10 cm in greatest dimension
T2b: Tumor limited to kidney, > 10 cm in greatest dimension
T3a: Tumor extends into the renal vein or its segmental branches, or invades the pelvicalyceal system, or perirenal and/or renal sinus fat but not beyond Gerota fascia
T3b: Tumor extends into vena cava below the diaphragm
T3c: Tumor extends into vena cava above the diaphragm or invades the wall of vena cava
T4: Tumor invades beyond Gerota fascia (including contiguous extension into ipsilateral adrenal gland)
Lymph node classification
Nx: Regional lymph nodes cannot be assessed
N0: No regional lymph node metastasis
N1: Regional lymph node metastases
Distant metastasis
M0: No distant metastasis
M1: Distant metastasis present
Stage cannot be fully assessed
Reference
Amin, M.B., Edge et al. AJCC Cancer Staging Manual. AJCC. 2017.
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