The calculator in question is the TNM Classification for Esophageal Adenocarcinoma. TNM stands for Tumor, Node, Metastasis, and it is a globally recognized system used for classifying the extent of spread of cancer. This specific TNM classification is applicable to patients diagnosed with esophageal adenocarcinoma.

The clinical utility of this calculator is to stage the cancer, which is crucial for determining the most appropriate treatment strategy and for predicting prognosis. The TNM classification takes into account the size and extent of the primary tumor (T), whether the cancer has spread to nearby lymph nodes (N), and whether it has metastasized, or spread, to other parts of the body (M).

There are no specific exclusion criteria for the use of the TNM classification for esophageal adenocarcinoma. However, it is not applicable to other types of esophageal cancer, such as squamous cell carcinoma, or to cancers in other parts of the body. It is also less useful in early-stage cancers where the extent of disease may not be fully assessable.

TNM classification for esophageal adenocarcinoma

# Criteria
 ## Tumor classification
A. Tx: Primary tumor cannot be assessed
B. T0: No evidence of primary tumor
C. Tis: High-grade dysplasia/carcinoma in situ
D. T1a: Tumor invades lamina propria or muscularis mucosae
E. T1b: Tumor invades submucosa
F. T2: Tumor invades muscularis propria
G. T3: Tumor invades adventitia
H. T4a: Tumor invades pleura, pericardium, azygos vein, diaphragm, or peritoneum
I. T4b: Tumor invades other adjacent structures, such as aorta, vertebral body, or airway
## Lymph node classification
J. Nx: Regional lymph nodes cannot be assessed
K. N0: No regional lymph node metastasis
L. N1: 1-2 regional lymph nodes metastases
M. N2: 3-6 regional lymph nodes metastases
N. N3: >= 7 regional lymph nodes metastases
## Distant metastasis
O. M0: No distant metastasis
P. M1: Distant metastasis present

# Conditions
- C and K and O
- (D or E) and K and O
- (D or E) and L and O
- F and K and O
- (F and L and O) or (G and (K or L) and O) or (H and (K or L) and O)
- ((D or E or F or G or H) and M and O) or (I and (K or L or M) and O) or ((D or E or F or G or H or I) and N and O)
- (D or E or F or G or H or I) and (L or M or N) and P
- true