The REMA score, or the Spanish Network on Mastocytosis score, is a clinical calculator used specifically for patients with suspected systemic mastocytosis. Systemic mastocytosis is a rare disorder characterized by an excessive accumulation of mast cells in various organs. The REMA score helps in the diagnosis of this condition by evaluating various clinical and laboratory parameters such as skin lesions, serum tryptase levels, and bone marrow biopsy results. 

The clinical utility of the REMA score lies in its ability to differentiate systemic mastocytosis from other conditions with similar symptoms, thus guiding appropriate treatment strategies. It is particularly useful in cases where the diagnosis is uncertain or when the patient presents with atypical symptoms. 

The REMA score may not be applicable or reliable in patients with other concurrent hematological disorders, as these may influence the parameters used in the score calculation. Additionally, it may not be suitable for use in pediatric patients as the score was developed and validated in adult populations.

Spanish Network on Mastocytosis score for systemic mastocytosis (REMA score)

# Description:
The REMA score, or the Spanish Network on Mastocytosis score, is a clinical calculator used specifically for patients with suspected systemic mastocytosis. Systemic mastocytosis is a rare disorder characterized by an excessive accumulation of mast cells in various organs. The REMA score helps in the diagnosis of this condition by evaluating various clinical and laboratory parameters such as skin lesions, serum tryptase levels, and bone marrow biopsy results. 

The clinical utility of the REMA score lies in its ability to differentiate systemic mastocytosis from other conditions with similar symptoms, thus guiding appropriate treatment strategies. It is particularly useful in cases where the diagnosis is uncertain or when the patient presents with atypical symptoms. 

The REMA score may not be applicable or reliable in patients with other concurrent hematological disorders, as these may influence the parameters used in the score calculation. Additionally, it may not be suitable for use in pediatric patients as the score was developed and validated in adult populations.
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# Inputs:
## Gender
A. Male (+1)
B. Female (-1)

## Urticaria and/or angioedema
C. None (+1)
D. Yes (-2)

## Presyncope and/or syncope
E. None (+0)
F. Yes (+3)

## Baseline serum tryptase
G. < 15 ng/mL (-1)
H. > 15 ng/mL (+2)
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# Scoring:
- If score <= 1, then Low probability of clonal mast cell activation disorder
- If score >= 2, then High probability of clonal mast cell activation disorder
- If score == 0, then Please make a selection)