The IPSET (International Prognostic Score for Essential Thrombocythemia) score is a clinical calculator used specifically for patients diagnosed with essential thrombocythemia, a rare chronic blood disorder characterized by the overproduction of platelets by megakaryocytes in the bone marrow. 

The IPSET score is used to stratify patients into risk categories (low, intermediate, and high) based on their risk of thrombotic events, which are common complications of essential thrombocythemia. The score takes into account factors such as age, thrombosis history, cardiovascular risk factors, and JAK2 V617F mutation status. 

The clinical utility of the IPSET score lies in its ability to guide treatment decisions and monitor disease progression. It helps clinicians to determine the intensity of treatment required, with higher scores indicating a need for more aggressive treatment strategies. 

There are no specific exclusion criteria for the use of the IPSET score, but it should be noted that it is only applicable to patients with a confirmed diagnosis of essential thrombocythemia. It is not intended for use in patients with other types of thrombocytosis or blood disorders.

IPSET score for essential thrombocythemia

# Criteria
 A. Age > 60 years (+1)
B. Cardiovascular risk factors (such as hypertension, diabetes mellitus, or current smoking) (+1)
C. JAK2V617F mutation (+2)
D. History of thrombosis (+2)

# Conditions
- score >= 3
- score == 2
- score <= 1
- score == 0

Development and validation of an International Prognostic Score of thrombosis in World Health Organization-essential thrombocythemia (IPSET-thrombosis).