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Diagnostic criteria for febrile neutropenia

Fever
Single oral temperature measurement of ≥ 38.3 °C (101 °F)
Temperature of ≥ 38.0 °C (100.4 °F) sustained over a 1-hour period
Neutropenia
Absolute neutrophil count ≤ 500/mcL
Absolute neutrophil count expected to decrease to < 500/mcL during the next 48 hours
Diagnostic criteria not met
Reference
Freifeld AG, Bow EJ, Sepkowitz KA et al. Clinical practice guideline for the use of antimicrobial agents in neutropenic patients with cancer: 2010 update by the infectious diseases society of america. Clin Infect Dis. 2011 Feb 15;52(4):e56-93.
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