Diagnostic criteria for chronic idiopathic intestinal pseudo-obstruction
Persistent or repetitive development of symptoms of serious bowel obstruction that may require hospitalization (such as abdominal distension, nausea and vomiting, abdominal pain) over a long period of time
Duration of symptoms ≥ 2 months for neonatal onset and
6 months for onset in infancy or later (including adults)
Gastrointestinal dilatation and air-fluid level on diagnostic imaging
No lesions mechanically blocking the gastrointestinal tract
No pathological abnormalities in the nerve plexuses on HE-stained full-thickness intestinal biopsy specimens
Megacystis microcolon intestinal hypoperistalsis syndrome and segmental dilatation of intestine are excluded
Secondary chronic intestinal pseudo-obstruction is excluded
Criteria not met
Reference
Mitsuru Muto, Hiroshi Matsufuji, Tomoaki Taguchi et al. Japanese clinical practice guidelines for allied disorders of Hirschsprung's disease, 2017. Pediatr Int. 2018 May;60(5):400-410.
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