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Is Marfans associated with arrhythmia

Answer

Marfan syndrome (MS) is associated with arrhythmias, particularly ventricular arrhythmias.

Pathophysiology

Clinical evidence

Management

In conclusion, Marfan syndrome is associated with arrhythmias, particularly ventricular arrhythmias, due to structural abnormalities in the cardiovascular system resulting from fibrillin-1 mutations. The management of MS involves medical therapy to slow the progression of aortic dilation and decrease the risk of dissection, as well as the use of antihypertensive medications and antiarrhythmic drugs for life-threatening ventricular arrhythmias.

References

1

Marfan syndrome

Medical management

Guidelines

Antihypertensive medications

Pathway
ACC/.../AHA 2022